Adamantinomatous craniopharyngioma: moving toward targeted therapies
نویسندگان
چکیده
منابع مشابه
Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma
Adamantinomatous craniopharyngiomas (ACPs) are the most common pituitary tumours in children. Although histologically benign, these are clinically aggressive tumours, difficult to manage and associated with poor quality of life for the patients. Several human and mouse studies have provided unequivocal evidence that the over-activation of the WNT/β-catenin signalling pathway underlies the molec...
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INTRODUCTION Craniopharyngioma of childhood are commonly cystic in nature. An intracystic catheter insertion and subsequent instillation of substances inducing cyst shrinkage seems a beneficial strategy avoiding additional morbidity in a highly vulnerable brain location. METHODS A systematic review of the medical literature was performed to identify potentially relevant, all languages article...
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ژورنال
عنوان ژورنال: Neurosurgical Focus
سال: 2020
ISSN: 1092-0684
DOI: 10.3171/2019.10.focus19705